Can I file a missing persons report on my sister?

Holy ****! Yes you should! My God, your sister is missing, you tried to find her, and her uncle doesn't know where she is? File a missing report! Do it so you have legal actions to finding her, or the Police can help you find her, you have no clue where she is right now, she might be kidnapped for God's sake, you wouldn't know right? File a report Girl! You've got no time to waste.